Preparation and Standardization of 0.1 M Sodium Nitrite (NaNO2) by using Sulphanilic acid in Pharmaceutical Analysis. Chemical Name: 0.1 M Sodium Nitrite (NaNO2) Reagents: 1.0 Sodium nitrite2.0 Sulphanilic acid3.0 Potassium bromide4.0 2M Hydrochloric Acid5.0 Starch iodide paper Preparation of 0.1 M Sodium Nitrite To make this solution, take 7.5 grams of sodium nitrite and dissolve … Read more
Preparation and Standardization of 0.05 M EDTA Solution by using disodium edetate and Eri Chrom Black T as an indicator in Pharmaceutical Labs. EDTA, which stands for Edathamil, or Ethylene diamine tetra acetic Acid, is a well-known substance used in managing and treating heavy metal toxicity. Preparation of 0.05 M EDTA Solution: To prepare a … Read more
Aim: To Prepare and standardize 0.05 M Iodine Solution by using As2O3 Name: 0.05 M Iodine solution Ingredients Required for Preparation and Standardization of 0.05 M Iodine Solution: How to Preparation and Standardization of 0.05 M Iodine Solution To Prepare this solution, you’ll need to follow these steps: How to Standardization of 0.05 M Iodine … Read more
Aim: The aim is to find out the normality of the given 0.1 M Ceric ammonium Sulphate. Requirements: Equipment: A special tube with a tap, a cone-shaped flask, and a small tube.Reagents: Ceric ammonium sulphate, Sulphuric acid, Arsenic trioxide, Sodium hydroxide, and some more sulphuric acid. Principle: We test Ceric ammonium sulphate by mixing it … Read more
Name: How to Preparare and Standardization of 0.1 M Disodium Edetate (EDTA Ingredients : 1. Disodium Edetate. 2. Calcium Carbonate 3. Eriochrome black – T 4. Ammonia – Ammonium Chloride Buffer pH10 (Mix 5.4 grams of NH4Cl + 35 milliliters of 10M NH3 solution & dilute to 100 milliliters with water.) 5 Hydrochloric Acid. How … Read more
Aim: To prepare and standardize 0.5 M sulfuric acid (0.5 M H2SO4). Principle: 1. This is carried out by aqueous acid-base titration based on a neutralization reaction. 2. This titration takes place between sulphuric acid (H2SO4) and sodium carbonate (Na2CO3). 3. Sodium carbonate, anhydrous is a primary standard substance that reacts with a secondary standard … Read more
Objective: The purpose of this experiment is to standardize 1.0 M Sulfuric Acid. Materials used for 1.0 M Sulfuric Acid: Equipment: Beaker, Funnel, Pipette, BuretteChemicals: H2SO4, Phenolphthalein solution, and Anhydrous sodium carbonate. Theory: Methyl orange is commonly used as an indicator in titrations. In an alkaline solution, methyl orange appears yellow and has the following … Read more
Preparation and Standardization of 0.1 M Sodium Hydroxide (NaOH) in the Laboratory. Reagents: 1 Sodium hydroxide 2 Potassium hydrogen phthalate 3 Phenolphthalein solution. Chemical Reaction Principle: In this process, we will directly measure the strength of potassium hydrogen phthalate by using sodium hydroxide. To find the endpoint, we’ll use phenolphthalein as an indicator. Let’s understand … Read more
In this experiment, we will focus on the preparation and standardization of a 1 M Sodium Hydroxide solution. Molarity and How to Prepare 1 M NaOH with Example: Example for factor calculation for standardization of 1 m NaOH:Na=23O=16H=1Total= 40 gm. Reagents Required for Preparation and Standardization of 1 M NaOH: 1 Sodium Hydroxide 2 Potassium … Read more
Name: Preparation and Standardization of 1.0 M Hydrochloric Acid in Pharmaceutical Laboratory. Reagents: Use the following reagents to prepare and Standardization of 1.0 M Hydrochloric Acid: 1 Hydrochloric Acid. 2 Anhydrous Sodium Carbonate 3 Methyl Red Method of Preparation of 1.0 M Hydrochloric Acid: To make 1.0 M hydrochloric acid, dilute 85.0 ml of concentrated … Read more
The Quality control test is to be done to check the build quality of the packaging materials in pharmaceuticals. The quality control officer is responsible for sampling and checking their quality as per given parameters. Once passing of all these parameters QC officer makes entries logbook and prepares a release note for further processing. Now … Read more
There are various Autoclave Qualification Tests that need to be done along with procedure and acceptance criteria. Autoclave works by using heat and pressure to kill the microorganisms such as bacteria and spores so it becomes very crucial or very important equipment for sterilization processes In this article we will go through the few prerequisites … Read more
The accelerated Stability Study method is developed to predict the stability and shelf life of products under normal or recommended storage conditions by different guidelines. These recommended methods are used to carry out a study of products under different accelerated conditions by using temperature, moisture, and light. As can say an accelerated stability study is … Read more
The major difference between HPLC and LCMS is that HPLC uses Non-volatile and Volatile buffers whereas LCMS uses Only volatile buffers. Common Difference between HPLC and LCMS/HPLC-MS HPLC full form is High-Performance Liquid Chromatography. It is a technique that is used to separate and analyze compounds in a mixture using liquid chromatography. It is a … Read more
Lead is a most undesirable impurity in pharma compounds and comes through the use of sulphuric acid, lead-lined apparatus, and glass bottles used for the storage of chemical materials so, we do a Limit Test for Lead to identify the acceptance level of lead in a sample. Limit test for lead Principle The limit test … Read more
The limit test for arsenic is based on the reduction of the arsenic in the arsenic state to the arsenic gas with zinc and hydrochloric acid. The arsenic gas stains the mercuric chloride paper yellow. The paper is dissolved in acid where the arsenic present as an impurity in the sample gets converted into arsenic … Read more