Learn About Standard Operating Procedure on IPA 70 % Preparation including their, Purpose, Scope, Procedure, frequency, and Annexures.
1.0 Purpose: To lay down the Standard Operating Procedure for the Preparation of 70 percent v/v Isopropyl Alcohol Solution.
2.0 Scope: This SOP applies to the preparation of 70 percent v/v Isopropyl Alcohol Solution.
3.0 Procedure: 3.1 Requisition for Isopropyl Alcohol 70 percentage Solution:
3.1.1 Prepare the Material Requisition for Isopropyl Alcohol, mentioning the required Quantity as per Annexure-II “Item Requisition Slip.”
3.1.2 Get the Requisition Approved by the Head of Production and Authorised by the Head of Quality Assurance.
3.1.3 Handover Authorised Material Requisition Slip to Warehouse Department.
3.2 Transfer and Storage of Isopropyl Alcohol Solution:
3.2.1 Ensure that the Stainless steel Container is Closed Properly.
3.2.2 Keep the S.S. Container on S.S. Trolley.
3.2.3 Transfer the Isopropyl Alcohol in S.S. Container to the Wash Room through a Dispensed RM Store.
3.3 Preparation of 70 % v/v Isopropyl Alcohol Solution:
3.3.1 Frequency: Whenever Required (At the Time of Product Change Over, Serial Cleaning, Recleaning, or At the Time of Qualification and Requalification of Dies and Punches).
3.3.2 Put on Safety Goggles, Nose Mask, and Hand Gloves.
3.3.3 Avoid any Spillage of Isopropyl Alcohol during Solution Preparation.
3.3.4 Take IPA and water in a 70:30 ratio for example, for the preparation of 3 liters of IPA take 0.900 Liters of Purified Water (use fresh purified water) in a Clean Stainless Steel Container and Add 2.100 liters of Isopropyl Alcohol.
3.3.5 Transfer the total quantity prepared of 70 % v/v Isopropyl Alcohol Solution to the specified Area in a closed condition.
3.3.6 Consume a total Quantity of 70% v/v Isopropyl Alcohol solution on the Same Day.
3.3.7 Record the details of the Solution Prepared as per Annexure “Preparation of 70 percentage v/v Isopropyl Alcohol Solution Record”.
3.3.8 Filter IPA 70% with sterilized 0.45 micron and 47 mm diameter membrane and pass through the vacuum pump assembly then store it in S.S. containers.
4.0 Abbreviations:
SOP – Standard operating procedure
SS – Stainless steel
v/v – volume by volume
No. – Number
% -Percentage
Annexure -I Preparation of 70 % isopropyl alcohol solution
Annexure -II Item Requisition Slip
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