MACO and NOEL Calculation for cleaning Validation

MACO and NOEL Calculation

MACO and NOEL calculations have great importance in the pharmaceutical industries. NOEL refers to “No observed effect level” and MACO is a “Maximum allowable carryover”. NOEL is used to determine MACO during cleaning validation. NOEL Calculation: NEOL is calculated by using LD50 and average. Adult dose. LD50 is a lethal dose (it may vary), considered an adult’s … Read more