0.1 N Perchloric Acid Preparation and Standardization

Preparation and Standardization of 0.1 N Perchloric acid (Non-Aquos by using glacial acetic acid and crystal violet solution as indicators in Pharmaceuticals.

Apparatus and Reagents Requirements:

Apparatus: Conical Flask, Volumetric Flask, Reflux condenser, Measuring cylinder, Burette, Pipette and Burette Stand.

Reagents:

• Perchloric acid
• Potassium hydrogen phthalate
• Anhydrous glacial acetic acid
• Crystal violet solution

Preparation of 0.1 N Perchloric acid

• Mix 85 ml of perchloric acid with 500 ml of anhydrous glacial acetic acid and 25 ml of acetic anhydride.
• Cool and make up the volume up to 1000 ml with glacial acetic acid.
• Allow the solution to stand for 24 hours and determine the water content before use.
• If the water content exceeds 0.05% add some more acetic anhydride.
• It also acts as an oxidizing agent so it should be handled with care.

Standardization of 0.1 N Perchloric acid

• Standardization: Weigh accurately about 0.35 gm of potassium hydrogen phthalate previously dried at 120°C and dissolved in 50 ml of glacial acetic acid.
• Add 0.1 ml of crystal violet solution and titrate with 0.1 N perchloric acid until the violet color changes to an emerald green color.
• Each ml of 0.1 N perchloric acid is equivalent to 0.02042 gm of potassium hydrogen phthalate

Calculation:

N₁V₁=N₂V₂

0.1 x 15 (Burrete Reading)= N₂ x 25 ml (solution Taken)

Result: The Normality of Perchloric Acid was found to be…?

FAQs