The Restricted Access Barrier System (RABS) enhances product control but reduces operator communication in aseptic manufacturing. The main aim of the RABS in pharmaceutical products is to ensure they are free of all contamination risks. During the early 1990s, new systems were developed to help sterile pharmaceutical manufacturers ensure contamination-free sterile products at a very … Read more
Injectable preparations, also known as parenteral preparations, are sterile formulations used for parenteral infusion or implantation. They are administered by injection to maintain sterility and prevent contamination by foreign matter, pyrogens, microorganisms, and bacterial endotoxins. These preparations must be made using methods that ensure sterility. Water for injection (WFI) is commonly used as a vehicle … Read more
Tablet excipients generally have no medicinal properties, although excipients are used to fill the drug’s bulk mass. Excipients also facilitate sustaining the drugs for a long time and help increase bioavailability in systemic absorption. Excipients might help in disintegration, lubrication, masking the test, and tablet hardness. The different types of Tablet excipients are explained below with … Read more
A capsule is a type of Unit dosage form in the pharmaceutical industry. It consists of small, cylindrical components made of either soft or hard gelatin, filled with a powder or liquid. Capsules are taken orally and are designed to release their contents after swallowing. They are commonly used for medications intended to be absorbed … Read more
Providing brief and accurate answers to interview questions is crucial for success in the selection process. While it can be challenging to find answers to certain questions, it is important to familiarize yourself with pharmaceutical interview questions and their corresponding answers, tailored to the position level, before the interview. Pharmaceutical Interview Questions and Answers for … Read more
Before starting to pack any product, the Production officer and Q.A. officer should check the area based on the line clearance checklist mentioned in the BMR/BPR records. While conducting line clearance, make sure to follow all points to ensure product quality and prevent contamination, mix-up, and cross-contamination. Line Clearance Checklist point for Primary Area: Related … Read more
The coating on tablets helps withstand the gastric environment and also has many advantages like masking the odor, color, and taste of a drug along with physical and chemical protection. Sometimes tablet’s quality may be improper if, the proper method and technique are not followed during the coating process. So to avoid these problems, we … Read more
Serialization in pharmaceuticals plays a vital role in securing product information, counterfeit, and falsified medicine that puts world public health at risk. These medicines are also not only ineffective but actively dangerous, inflicting adverse reactions or even death. What is more, these counterfeit medicines are also factory-made in multiple locations, e.g., chemical synthesis in one … Read more
Compression machines are used to compress the powder or granules into uniform size and weight. The machine and its tools are key in this process. Therefore, taking good care of and lubricating these tools is extremely important in the pharmaceutical industry. You may also read: about Tablet defects, Capsule defects, and Solid dosage form Different … Read more
Sometimes issues happen during the manufacturing process of tablets, and we call them tablet manufacturing defects. Below is a Detailed discussion on Tablets Manufacturing Defects and Remedies that help to encounter these situations. So to provide and maintain the quality of products, tablets should be free from such visual defects. A pharmaceutical company that manufactures … Read more