Learn the differences between primary, secondary, and tertiary pharmaceutical packaging materials with practical examples of bottles, blister packs, cartons, vials, shippers, and pallets used in the pharma industry.
Tablet presses or Compression machines are mechanical devices that compress granulated powders into uniform tablets for pharmaceuticals and other solid-dosage products. These machines force material between matching upper and lower punches seated in a die cavity to fuse it into a solid form. In operation, the lower punch first lowers into the die to create … Read more
Sometimes, issues occur during the tablet manufacturing process; these are known as tablet manufacturing defects. Below is a detailed discussion of tablet manufacturing defects and their remedies, which helps in addressing these issues. To ensure and maintain product quality, tablets should be free from such visual defects. A pharmaceutical company that manufactures medicines may face … Read more
The Why-Why analysis is considered to be a problem-solving approach that is mainly incorporated within the pharmaceutical industry so as to get to the root of the problems. It is a basic technique in which the why is asked Frequently until the real problem is found. This applies to the why-why technique the root cause … Read more
In Pharmaceuticals Packaging mainly two types of foil (Aluminium and PVC/PVDC) are used in the packaging department. So, Calculating the exact required quantity of foil for a particular lot is quite challenging for Professionals working in the Pharmaceutical manufacturing area. So, Questions arise How much quantity of printed aluminium foil and base foil is required … Read more
Tablets are solid dosage forms that are manufactured worldwide in the pharmaceutical industry. These are manufactured by molding or by compression method. Tablets or capsules come in the solid dosage form categories. Examples of solid dosage forms include tablets, capsules, powders, dry powders, and sachet. What are Tablets in Pharmaceuticals? Tablets are unit, solid dosage forms that contain one … Read more
Isolator in pharmaceuticals has a significant place in the production of sterile products because of their decontaminated environment. They meet Grade A conditions and provide continuous isolation from its interior to the external environment. The Evolution of Aseptic Processing If we talk about their Journey, aseptic processing has been quite interesting, taking us from traditional … Read more
In pharmaceutical manufacturing, coating tablets requires careful attention to detail to prevent issues like tablet twinning. Twinning is common with capsule-shaped tablets, where two tablets stick together, resembling conjoined twins. This discussion focuses on tablet coating specialists and quality control experts, explaining the causes and solutions for tablet twinning. Tablet Twining: Understanding the Defect When … Read more
In the pharmaceutical industry, ensuring the quality and integrity of sieves/Screens used in the manufacturing process is very important. Sieves are widely used to get desired particles size. To assess the integrity of sieves accurately, a specialized kit is used. This kit consists of various tools and procedures designed specifically for sieve inspection. In this … Read more
Double Cone Blender equipment is used in pharmaceuticals to mix Excipients, chemicals, and cosmetics to get a homogeneous mixture of dry powders and granules. The principle of the double cone blender is based on the mechanical mixing that occurs due to tumbling motion. The double-cone blender is constructed by welding two cone-shaped sections at their … Read more
The sugar coating of tablets process involves building up layers of coating materials on tablet cores by repetitively applying a coating solution or suspension and drying off the solvent. Sugar coating insulates and masks the color and texture of the core of the tablet. Here in this article, you will learn about the steps of … Read more
The procedure is applicable to the general procedure for filling the vaccine in the manufacturing area. Preparation of Primary packaging material for filling: Preparation of Filling Machine parts : Note: If required take the change over to the required format size 2ml, 3ml, or 5 ml format.Wash and prepare filling machine accessories and pack the … Read more
Equipment capacity means the minimum and max working capacity of any equipment that can be easy to operate with its predefined limit to get higher output. In pharmaceutical Equipment capacity calculation factor depends on the Bulk density of the excipients that are used in the granulation process. Factor affecting the equipment capacity Below are the … Read more
In today’s Pharmaceutical industries, the Granulation Technique is highly employed to get better Quality granules. Granulation is the act or process of forming or crystallizing into grains. Granules typically have a size range between 0.2 to 4.0 mm, depending on their subsequent use. Synonym “Agglomeration“: Agglomeration processes or, in a more general term, particle size … Read more
In order to achieve effective coating results, a sufficient amount of tablets must be placed in the coating pan. To get a consistent coating, the coating machine pan’s capacity should be estimated. Different coating issues may result from using insufficient amounts of tablets to coat inside the coating pan. so let’s understand how to calculate … Read more
A Hammer Mill machine is widely used in the Pharmaceuticals and Food industries to cutting Materials into small fragments or small pieces (Also called Size Reduction). The main component of a hammer mill is a row of hammers that are hinged on a central shaft and contained in a strong metal container. Size reduction is … Read more