Name: Preparation and Standardization of 1.0 M Hydrochloric Acid in Pharmaceutical Laboratory. Reagents: Use the following reagents to prepare and Standardization of 1.0 M Hydrochloric Acid: 1 Hydrochloric Acid. 2 Anhydrous Sodium Carbonate 3 Methyl Red Method of Preparation of 1.0 M Hydrochloric Acid: To make 1.0 M hydrochloric acid, dilute 85.0 ml of concentrated … Read more
The Quality control test is to be done to check the build quality of the packaging materials in pharmaceuticals. The quality control officer is responsible for sampling and checking their quality as per given parameters. Once passing of all these parameters QC officer makes entries logbook and prepares a release note for further processing. Now … Read more
There are various Autoclave Qualification Tests that need to be done along with procedure and acceptance criteria. Autoclave works by using heat and pressure to kill the microorganisms such as bacteria and spores so it becomes very crucial or very important equipment for sterilization processes In this article we will go through the few prerequisites … Read more
The accelerated Stability Study method is developed to predict the stability and shelf life of products under normal or recommended storage conditions by different guidelines. These recommended methods are used to carry out a study of products under different accelerated conditions by using temperature, moisture, and light. As can say an accelerated stability study is … Read more
The difference between High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography–Mass Spectrometry (LCMS) with schematic diagram comes down to what each technique does. HPLC separates and analyses compounds in a mixture. LC-Mass Spectrometry (MS) adds mass spectrometry to identify and quantify them. LC-MS is more sensitive but needs trained analysts. HPLC with Ultraviolet (UV) detection can … Read more
Lead is a most undesirable impurity in pharma compounds and comes through the use of sulphuric acid, lead-lined apparatus, and glass bottles used for the storage of chemical materials so, we do a Limit Test for Lead to identify the acceptance level of lead in a sample. Limit test for lead Principle The limit test … Read more
The limit test for arsenic is based on the reduction of the arsenic in the arsenic state to the arsenic gas with zinc and hydrochloric acid. The arsenic gas stains the mercuric chloride paper yellow. The paper is dissolved in acid where the arsenic present as an impurity in the sample gets converted into arsenic … Read more
The Limit Test for Sulphate is designed to determine the allowable limit of Sulphate contained in a sample. Principle: The principle for the limit test of Sulphate is based on the reaction of soluble Sulphate with barium chloride in the presence of dilute hydrochloric acid to form barium Sulphate which appears as turbidity with a … Read more
A limit test for chloride is done to identify the impurity in the compounds by comparing the test solution against the standard solution. The chloride limits test is only designed to identify and control the impurity present in the compounds. Limit Test for Chloride Principle The limit test for chloride is based on the reaction … Read more
The limit test for iron refers to a type of analytical chemistry test used to determine the concentration of iron in a sample. This test is often performed in the laboratory as part of a larger suite of tests to determine the chemical composition of a substance.In a limit test for iron, a known volume … Read more
In pharmaceutical analysis, a limit test is a type of analytical test used to determine impurity in a substance whether a substance is present in a sample at a concentration above or below a specified limit. Limit tests are often used to ensure that a substance meets certain quality standards or regulatory requirements. Definition The … Read more
Quality control equipment is widely used in pharmaceuticals for the testing of drugs as per given standards. The subject of analytical instruments has grown more complex recently. In order to get more precise results, personal computers and microcontrollers have been added to analytical equipment in modern times. A chosen few of these instruments are also … Read more
The High-Performance Liquid Chromatography (HPLC) column is the heart of the system. It holds the stationary phase that separates sample components. This article explains the various types of HPLC columns: guard, derivatizing, micro (capillary), analytical and preparatory columns, and what each one does in the analysis. This article covers the various types of HPLC columns … Read more
Aim: Methyl Orange Indicator Preparation | How to make w/v methyl orange Requirements: Glasswares: Burette, burette stand, conical flask, volumetric pipette, beaker, measuring flask, funnel, glass rod, wash bottle, storage container, etc. Chemicals: Methyl orange, Ethanol 20 ml, and Distilled water. Procedure for Methyl Orange Indicator preparation Related Post: Preparation and Standardization of 0.1 N HCl
Preparation and standardization of 0.1 N HCl: dilute 8.50 ml HCl to 1000 ml, then titrate against sodium carbonate with methyl orange and calculate normality.
Both humidity and relative humidity refer to the amount of water vapour in the air, however, they are not the same. Humidity is the absolute amount of water vapour in the air, whereas relative humidity is the amount of water vapour in the air in comparison to the maximum amount of water vapour the air might … Read more