For high-shear mixing, the Silverson homogenizer is highly used by many industries over the last 60 years. It is able to mix liquid to liquid and liquid to solid at the speed of up to 8000 r.p.m. In this article, we will discuss the Silverson mixer, its applications, principles, construction, working, advantages, and limitations. Principle: … Read more
Turbine Mixture is the most common equipment that is used in various industries for mixing purposes. It is very effective in the mixing of highly viscous materials. In this article, you will learn in detail about their principle, working, construction, application, advantage, and disadvantages. Principle of Turbine Mixer The principle of Turbine Mixer works on … Read more
Propellers are mechanical devices that are used to mix liquid materials by using blades. A propeller normally contains a number of blades A three-bladed design is generally used The marine type propeller is similar to the blades of a table fan or ceiling fan. They may be either right or left-handed depending on the direction … Read more
The Sigma Blade Mixer is one of the most popular mixers for blending and kneading materials with high viscosity. It is a double-arm kneader mixer used in handling high-viscosity materials. Principle behind the Sigma Blade Mixer The principle involved in these mixers, which handle highly viscous materials, depends on shearing and convecting generated by interlocking … Read more
The Ribbon Blender is a mixing device that operates on the principle of shear and convective mixing. Principles of Ribbon Blenders: Related: Size Reduction Construction of Ribbon Blenders: A ribbon blender consists of a U-shaped horizontal trough or shell that contains a helical double-ribbon agitator rotating inside it. The agitator’s shaft is positioned at the … Read more
Size reduction refers to the process of reducing the size of drugs into smaller particles or fine powder. It involves cutting or breaking particles of solids into smaller pieces. Size reduction becomes necessary when the starting material is too coarse and the desired final product needs to be in the form of a fine powder. … Read more
Size Separation involves the separation of a mixture containing particles of various sizes into two or more portions. This can be done through the use of screening surfaces or by shifting the mixture. It is also commonly known as sieving, sifting, or screening. The technique of size separation is based on different physical properties of … Read more
Air Separator is a pneumatic device that sperate the materials based on their size with the help of air current. This sperate the materials of lighter density from those of greater density and smaller size particles from the bigger ones. Air Separator Principle: The air separator operates based on a similar principle as the cyclone … Read more
Schedule M was incorporated by the Drug and cosmetic act of 1940 in 1988. Schedule M is also known for Good manufacturing practices. But earlier there were no rules and regulations that dictated us to know, How is our pharmaceutical building, location, premises, water system, construction area, warehouse, etc. Introduction to M Schedule Schedule M … Read more
The sieving technique is used widely to separate fine powder from coarse powder by utilizing sieves of specific sizes. By passing the powdered material through a sieve, we can determine the level of separation. Sieves are numbered for easy distinction between them. Working & Construction Size separation of powder occurs as the powdered material passes … Read more
In the pharmaceutical industry, ensuring the quality and integrity of sieves/Screens used in the manufacturing process is very important. Sieves are widely used to get desired particles size. To assess the integrity of sieves accurately, a specialized kit is used. This kit consists of various tools and procedures designed specifically for sieve inspection. In this … Read more
The Elutriation Tank is designed to achieve size separation of particles by using the distinct densities of fine and coarse particles. So to do this elutriating tank is used to effectively separate these particles. in this article, we will discuss Elutriation Method, Principle, Working, Construction, Advantages, and Disadvantages. Principle of the Elutriation Tank: The elutriation … Read more
The Bag filter works to enhance the air quality and prevent the loss of powder in pharmaceutical production. In pharmaceutical manufacturing, the processing of highly potent drugs like hormones, vitamins, antibiotics, etc., generates lots of powder, which can lead to hazards. Various processes, including screening, blending, mixing, drying, granulating, tableting, compression, and packaging, contribute to … Read more
Pharmaceutical Packaging is an art, and technology to enclose and safeguard products during their distribution, storage, sale, and use. It contains the process of designing, evaluating, and producing packages. In pharmaceuticals, packaging provides several essential functions, including presentation, protection, identification, information, convenience, compliance, integrity, and stability of the product. Functions of Pharmaceutical Packaging: Factors Affecting … Read more
The Quality control test is to be done to check the build quality of the packaging materials in pharmaceuticals. The quality control officer is responsible for sampling and checking their quality as per given parameters. Once passing of all these parameters QC officer makes entries logbook and prepares a release note for further processing. Now … Read more
In pharmaceuticals, the solubility of drugs plays a very important role in determining their efficacy and bioavailability. Poor solubility can lead to reduced absorption, irregular blood concentration levels, and inadequate therapeutic outcomes. To overcome these types of problems, scientists and researchers have developed various techniques to enhance Drug Solubility. This article explores the different methods … Read more