Quality control equipment is widely used in pharmaceuticals for the testing of drugs as per given standards. The subject of analytical instruments has grown more complex recently. In order to get more precise results, personal computers and microcontrollers have been added to analytical equipment in modern times. A chosen few of these instruments are also … Read more
Pharmaceutical organizations required Standard grads equipment for the different sections to carry out processes or manufacturing of products. A new pharma manufacturer doing a hard struggle to find and prepared a list of Pharma equipment to purchase as per their capacity requirement. So the common list of pharma equipment is given below for the different … Read more
SCADA stands for Supervisory Control and Data Acquisition. It is a collection of software and hardware components that enable local and remote plant monitoring and control. Furthermore, the SCADA analyzes, collects, and processes data in real-time. SCADA Functions Users can communicate with field devices such as pumps, valves, motors, sensors, and more using human-machine interface … Read more
FBD refers to a Fluidized bed dryer that is commonly used in the pharmaceutical industry to reduce the moisture content of pharmaceutical granules. It is the best technique used by the manufacturer to produce a good quality product. However, with time, new advanced techniques are introduced to replace old like; in case of FBD, a … Read more
Track and trace system in pharmaceuticals is a process of determining the current and past history of products through their unique ID, or their properties. It helps the manufacturer to get information about false or copied products in the market. Track system is simply to know about the current and past location of any serialized … Read more
Many of the gases, liquids, and powders utilized in pharmaceutical product formulation are extremely flammable, explosive, reactive, and/or poisonous. So Fire Safety Practices must be followed to ensure the overall safety of pharmaceuticals. Furthermore, many of the processes used in pharmaceutical plants – from delivery through reactor processing to filtration, drying, milling /micronizing, combining, and … Read more
Sometimes we may confused when it comes to understanding the difference between moisture content and Loss on Drying (LOD). To clear your doubts, please read the entire section of this post. Firstly, let’s discuss about moisture analyzers. A moisture analyzer is used to determine the water content in a sample. Then a few questions arise … Read more
A Metal detector is used to find out and remove small pieces of ferrous, non-ferrous, and SS during tablet compression in pharmaceuticals. Many times, Such types of metal may be entered into the product during the process, for example, worm sieve wires. This is where the metal detector comes into the role to removes such types of … Read more
pH meter is used to measure the acidity and alkalinity of a solution by measuring Hydrogen ion concentration in a solution. pH Meter Calibration is required at regular intervals or as per the defined frequency to maintain its accuracy. Here, we will discuss the pH meter principle, ph meter electrode, Range of pH, Calibration, Key … Read more
High-Performance Liquid Chromatography (HPLC) is used in pharmaceuticals for the analysis of drug mixture and their components. HPLC is reverse-phase Liquid Chromatography. This technique is used for thermal labile, high molecular weight peptides, and non-volatile compounds. The main purpose of HPLC is used to examine the mixture for its identification, impurities, and purification. The mixture … Read more
1.0 OBJECTIVE: To lay down a procedure for cleaning, operation, and calibration of friability test apparatus. 2.0 SCOPE: This procedure is applicable to the cleaning, operation, and calibration of the friability test apparatus used in pharmaceutical manufacturing. 3.0 RESPONSIBILITY: Officer, Executive – Production DepartmentManager – Production Department, QA Officer – In the process 5.0 PROCEDURE: 5.1 Cleaning5.1.1 Remove … Read more
The term HEPA means “High-efficiency Particulate Air,” sometimes called “High-Efficiency Particulate Arrestance,” and what that basically means is that it’s a special kind of filter that captures microscopic particles. A HEPA filter removes particles like dirt, pollen, spores, pet dander, bacteria, smoke, and particulates that come from outdoor pollution. Types of HEPA Filters? Another issue … Read more
Blenders play a significant role in mixing ingredients in pharmaceuticals. Choosing the right types of blenders is crucial, so we select specific blenders among the different types available for use in pharmaceutical manufacturing according to our requirements. Blenders are used in pharmaceuticals after the granules manufacturing in the production section. Granules are mixed with different … Read more
Air is one of the major sources of contamination for pharmaceutical products. That is why the design, monitoring, and maintenance of the AHU (Air Handling Unit) are essential to increase its efficiency and capacity as per GMP (Good Manufacturing Practices). Important tips are given here to follow good practices for an Air Handling Unit. Tips … Read more
The Restricted Access Barrier System (RABS) enhances product control but reduces operator communication in aseptic manufacturing. The main aim of the RABS in pharmaceutical products is to ensure they are free of all contamination risks. During the early 1990s, new systems were developed to help sterile pharmaceutical manufacturers ensure contamination-free sterile products at a very … Read more
The Friability test helps measure the powder lost from tablet surfaces during handling and transport. This test is typically done on uncoated tablets. The parallel to friability test, tablets hardness, is also tested to know the strength of tablets which is more important for drugs to withstand throw-out their lifecycle. However, hardness is not only a parameter … Read more