Difference between Static and Dynamic Pass box

Difference between Static and Dynamic Pass box

Pass boxes are cleanroom systems used to transfer materials from one area to another cleaned area through a controlled environment. Pass boxes help control contamination and cross-contamination by passing particular matter present on the surface of materials that are to be transferred. These materials automatically pass through the filter present on the pass box during … Read more

Vernier Caliper measurement and operation in Pharma

vernier caliper

Vernier caliper is used widely in pharmaceutical and other industries for Accurate Measurement of any products and part of the equipment is essential to know the actual dimension. So to measure the dimension first you have to know about, the vernier caliper Definition, procedure, parts, operation, cleaning, error solutions, and purpose. Vernier Caliper Definition: The Dial … Read more

Calibration of UV-visible spectrophotometer

calibration UV-visible spectrophotometer

UV-visible spectrophotometer are widely used in the pharmaceutical industry for analyzing and quantifying various drug substances. It is important to ensure that these instruments are calibrated accurately and regularly to obtain reliable and accurate results. In this guide, we will take you through the calibration procedure and parameters of a UV spectrophotometer. Calibration of UV-visible … Read more

Weighing Balance Calibration in Pharmaceutical

Calibration of weighing balance

By definition, Weighing balance calibration is a process of verifying the accuracy and precision of a weighing balance used in pharmaceutical manufacturing. It involves comparing the measurement of the balance to a known standard to ensure that it is providing accurate results. In the pharmaceutical industry, we perform monthly calibration on weighing balances to verify … Read more

Design Qualification in Pharmaceutical industry

Design Qualification

A Design Qualification comes to the role after the Design Specification as well as User requirements specification are finalized. Once URS is finalized follow the given specification requirement in the purchase order (PO). After checking it properly, the engineering, and production department will prepare the design qualification, which includes drawing, calculation, symbols, and other design … Read more

Pharmaceutical AHU and HVAC Components

Good Practices For Air Handling Unit

In pharmaceutical industries AHU and HVAC play an essential role in controlling microorganism-free environments by supplying fresh air. The quality of pharmaceutical products is dependent on hygiene within the industry. Preventing the spread of microorganisms through the air is highly significant. Whether it’s during laboratory development or manufacturing activities, maintaining a clean and suitable room atmosphere is … Read more

Rapid Mixture Granulator(RMG); Working and Principle

Rapid mixture Granulator machine

A Rapid mixture granulator (RMG) is used in mixing, agitation, and shear mixing (to break internal molecular force). It is used in pharmaceuticals to make granules. The components of the RMG (impeller and chopper) are highly responsible for the wet granulation process. Components of RMG: Rapid mixture granulator components are as follows: The impeller and chopper are responsible … Read more

Multimill; Working and principle

Multimill

Multimill is used widely in pharmaceuticals (granulation section), cosmetics, chemicals, and bulk drugs for cutting granules into small particle sizes by using cutting, Pulverization, and hammering mechanisms. Components of multi-mill: 1. Hopper inlet The hopper is used to feed products to the mill. 2. Milling chamber The milling chamber contains a screen to reduce particle … Read more

Colloidal Mill; Working and Principle

Colloidal mill

A colloidal mill is used to break down a mixture that contains Suspended solid particles to make a homogeneous mixture. So it is used in a wide range of pharmaceuticals and other industries to make a suspension. Working Principle of Colloidal Mill: The colloidal mill works on Shearing by using a rotor/ stator. By using shearing force its … Read more