These days, choosing the right material for constructing manufacturing equipment parts is an important aspect. Manufacturing equipment is usually made of stainless steel, with various alloys in SS such as 304, 316, and 316L. These alloys are widely used and valuable. Type 304 is a commonly used alloy in the group of steel known as … Read more
Before starting to pack any product, the Production officer and Q.A. officer should check the area based on the line clearance checklist mentioned in the BMR/BPR records. While conducting line clearance, make sure to follow all points to ensure product quality and prevent contamination, mix-up, and cross-contamination. Line Clearance Checklist point for Primary Area: Related … Read more
Autoclave validation is required to get effective Sterilization to ensure good product quality and also sterility of glassware and media used for analysis is very important for product manufacturing. Ineffective autoclave validation may cause deviation in sterility and it may lead to a false result. So data loggers play a very important role in recording the … Read more
Learn about the Standard operating procedure for “Entry and Exit Procedure in Pharmacautical” along with Purpose, Scope, Responsibility, Instruction, Procedure, Entry procedure for employees, Exit procedure for the employees, and Entry and Exit procedure for visitors. 1.0 Purposes: 1.1 Lay down the standard operating procedure for the entry-exit procedure in pharmaceuticals. 2.0 scope: 2.1 This SOP applies to all personnel, … Read more
In pharmaceutical industries AHU and HVAC play an essential role in controlling microorganism-free environments by supplying fresh air. The quality of pharmaceutical products is dependent on hygiene within the industry. Preventing the spread of microorganisms through the air is highly significant. Whether it’s during laboratory development or manufacturing activities, maintaining a clean and suitable room atmosphere is … Read more
A Rapid mixture granulator (RMG) is used in mixing, agitation, and shear mixing (to break internal molecular force). It is used in pharmaceuticals to make granules. The components of the RMG (impeller and chopper) are highly responsible for the wet granulation process. Components of RMG: Rapid mixture granulator components are as follows: The impeller and chopper are responsible … Read more
A multimill is one of the universal machines used in the granulation section, which allows for obtaining both wet and dry granulations. Learn about its operating principle, the main details, their interaction, the engine speed range, and the dependence of the material passing through the sieve openings on the sieve size and the position of the knives.
Learn about SOP on Product waste, its collection and disposal as per the pharmaceutical GMP standards, along with Annexure.
Learn how a colloid mill works in pharmaceutical manufacturing — principle, components, process flow, troubleshooting, and maintenance explained.
A disintegration test apparatus: a brief explanation of the diagram and main elements, as well as the mechanism of the disintegration process itself. Moreover, the present article describes apparatus types, discusses the disintegration test procedure, calibration requirements, and time limits according to USP, BP, IP, and Ph. Eur. – useful information for quality control analysts, production managers, and students who study the characteristics of medicinal forms and want to determine the disintegration time of tablets or capsules.
Tablet coating defects are a real headache in pharmaceutical manufacturing. When the coating process isn’t properly controlled, the consequences ripple through quality, appearance, and stability—sometimes all three at once. This guide breaks down the 10 most common tablet coating problems you’re likely to encounter: blistering, cratering, cracking, picking, pitting, blooming, blushing, roughness, colour variation, and logo bridging. For each one, we cover what’s actually causing it and what you can do to fix it—practical troubleshooting grounded in real manufacturing experience, not just theory.
Learn how to use a leak test apparatus in pharmaceutical manufacturing. This guide covers everything from equipment operation and calibration to testing procedures, safety, documentation, and GMP compliance — so you can catch leaks accurately and keep product quality where it needs to be.
Understand water system validation in pharmaceutical manufacturing with a step-by-step overview of validation phases, qualification protocols, documentation, and ongoing GMP compliance in 2026.
Effluent Treatment Plants (ETPs) in pharmaceutical manufacturing treat wastewater containing APIs, solvents, and high pollutant loads to ensure regulatory compliance and environmental protection.
Quick Answer The Drugs and Cosmetics Rules, 1945 categorize drugs, cosmetics and medical devices under Schedules A to Y. Every schedule is for a particular purpose, application forms (Schedule A), lab fees (Schedule B), biological products (Schedule C), GMP for pharmaceuticals (Schedule M), GMP for ASU drugs (Schedule T), and labelling of narcotics (Schedule H, … Read more
Standard Operating Procedure of Camera Vision System & Pinhole Detector-Setup, Operation, Challenge Testing, Cleaning & in the process Verification in Pharmaceutical Blister/ alu alu machine.